Dr. Grumpy: "What dose are you up to now?"
Mr. Math: "Um, I've got the 25mg pills, and I'm taking 4 of them, twice a day."
Dr. Grumpy: "That's a standard dose, you should be okay."
Mr. Math: "I dunno. I read some scary stuff online about taking so many pills, and I'd like to change."
Dr. Grumpy: "How about if I change you to the 100mg pills, and you take one twice each day?"
Mr. Math: "Oh, that's fine. Thank you for working with me on this."