tag:blogger.com,1999:blog-5883634615775822475.post4607588793897648401..comments2024-03-26T16:46:21.764-04:00Comments on Doctor Grumpy in the House: Mickey? Can you hear me now?Grumpy, M.D.http://www.blogger.com/profile/09858110332436246760noreply@blogger.comBlogger25125tag:blogger.com,1999:blog-5883634615775822475.post-48741541701434058972011-03-09T14:18:33.426-05:002011-03-09T14:18:33.426-05:00Well at least we have a solution to the age old, h...Well at least we have a solution to the age old, heartbreaking situation of tinnitis in rats...pharmacy chickhttp://pharmacychick.blogpharm.comnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-86358821576265480982011-03-09T11:52:37.106-05:002011-03-09T11:52:37.106-05:00How do you know rat hears ringing: take single-cel...How do you know rat hears ringing: take single-cell recordings of the brain region that processes hearing (temporal lobe i believe) while in an isolated acoustic chamber<br /><br />How do you ask the rat if ringing stops: train it to press a lever when it doesn't hear ringing, and train it not to press a lever when it does, observe behaviour<br /><br />How do you know if the ringing bothers the rat: you don't!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-63055152725048123122011-03-08T22:27:13.072-05:002011-03-08T22:27:13.072-05:00I haven't read the article, but I'm assumi...I haven't read the article, but I'm assuming you did. So how do they explain how they measure tinnitus in rats?The Motherhttps://www.blogger.com/profile/15157821003454766570noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-10364086574341056932011-03-08T20:15:35.455-05:002011-03-08T20:15:35.455-05:00so would adrenal stimulation be a way of driving v...so would adrenal stimulation be a way of driving vermin rats away?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-56168378576253082922011-03-08T19:59:59.317-05:002011-03-08T19:59:59.317-05:00I've tinnitus since I was child... it doesn...I've tinnitus since I was child... it doesn't bother me or drive me to distraction, since the sound is not that loud. A clinical trial would be intresting, to see i f it would help.Aleighnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-22814700970043176222011-03-08T19:26:12.373-05:002011-03-08T19:26:12.373-05:00"I can picture it now: Little rat listens to ...<i>"I can picture it now: Little rat listens to the tones to check its<br />hearing and raises his paw or a<br />wee high five when he hears"</i><br /><br />DawwwwwwwJuleshttps://www.blogger.com/profile/17260044140161891802noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-77310001449564184052011-03-08T19:04:36.768-05:002011-03-08T19:04:36.768-05:00LOL at "I do not know, go ask your mother&quo...LOL at "I do not know, go ask your mother"<br /><br />This blog is always a bright spot.Carahttps://www.blogger.com/profile/01537829992032436613noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-48723721942071430542011-03-08T16:34:43.330-05:002011-03-08T16:34:43.330-05:00Could be that they measured activity in the brain ...Could be that they measured activity in the brain to figure out if they had ringing in the ears. Have they ever done that in people? Electrical activity or PET scans? Seems to me that if you heard ringing in your ears your brain has to register it somehow so you "know" your ears are ringing.Brittneyhttps://www.blogger.com/profile/06304750174259826560noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-75124600755066800382011-03-08T15:15:22.527-05:002011-03-08T15:15:22.527-05:00Vagus nerve stimulation always works for me. Whene...Vagus nerve stimulation always works for me. Whenever I experience tachychardia I do my vagus nerve stimulation, works for acid reflux too. I never heard about the tinnitus.Packerhttps://www.blogger.com/profile/10790343423937405624noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-20354095628761895332011-03-08T14:06:24.364-05:002011-03-08T14:06:24.364-05:00I can picture it now: Little rat listens to the to...I can picture it now: Little rat listens to the tones to check its<br />hearing and raises his paw or a<br />wee high five when he hears.donnanoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-90962344483411032092011-03-08T12:13:08.235-05:002011-03-08T12:13:08.235-05:00I knew at least one reader would pick up on that.I knew at least one reader would pick up on that.Grumpy, M.D.https://www.blogger.com/profile/09858110332436246760noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-4649696501094711852011-03-08T12:12:00.716-05:002011-03-08T12:12:00.716-05:00@ Grumpy's last comment:
Sorry, fresh out.
N...@ Grumpy's last comment:<br /><br />Sorry, fresh out.<br /><br />Now, pardon me while I curtail my Walpoling activities. I'm feeling a bit peckish.ndenunznoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-55006337991999526732011-03-08T10:59:28.916-05:002011-03-08T10:59:28.916-05:00Heck, for good cheese, you could GIVE me tinnitis....Heck, for good cheese, you could GIVE me tinnitis.Not Househttp://iamnothouse.comnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-80638931587525278312011-03-08T10:43:41.098-05:002011-03-08T10:43:41.098-05:00guess it's not artisanal.guess it's not artisanal.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-72603101265893099912011-03-08T10:40:24.603-05:002011-03-08T10:40:24.603-05:00Venezuelan Beaver Cheese.Venezuelan Beaver Cheese.Grumpy, M.D.https://www.blogger.com/profile/09858110332436246760noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-30880666113089774332011-03-08T10:37:56.268-05:002011-03-08T10:37:56.268-05:00"They can't pay volunteers much, but do o..."They can't pay volunteers much, but do offer unlimited cheese."<br /><br />what kind of cheese?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-4565636523856257232011-03-08T10:22:52.197-05:002011-03-08T10:22:52.197-05:00I was glad to learn from an article in Science New...I was glad to learn from an article in Science News a few years ago that tinnitus is not an artifact of a damaged nerve or something, but it is a real sound in your ear. Caused by feedback or something, but it is an actual sound that can be picked up by a teeny tiny mic.SB Gypsyhttps://www.blogger.com/profile/14104522586390324382noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-55057620077742662902011-03-08T08:20:57.751-05:002011-03-08T08:20:57.751-05:00I found that article particular when I read about ...I found that article particular when I read about it a while ago...still, as someone who's suffered from tinnitus since birth (now being over 30 y.o.), I hope something can come from that initial spark... we'll see.<br />Worst-case-scenario: I'll gladly take the cheese man.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-35692675682419251442011-03-08T07:44:32.251-05:002011-03-08T07:44:32.251-05:00I think they just judge actions the rats do therea...I think they just judge actions the rats do thereafter. If the drug works, the subject steps on the remote button to turn down the volume to "The Price is Right."CrownedwithVictoryhttps://www.blogger.com/profile/15139186237180334168noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-9649815498081184622011-03-08T07:37:49.552-05:002011-03-08T07:37:49.552-05:00All dairy products, including cheese, are bad for ...All dairy products, including cheese, are bad for rodents.<br /><br />Tinnitus is extremely stressful. There is no such thing as peace and quiet, ever. Ringing, ringing 24/7 with no relief. It makes migraines worse than they would otherwise be.RSDSnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-50836205861848299432011-03-08T07:35:31.513-05:002011-03-08T07:35:31.513-05:00Maybe they turn their heads one way or another? I ...Maybe they turn their heads one way or another? I do not know. Go ask your mother.Grumpy, M.D.https://www.blogger.com/profile/09858110332436246760noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-62398450337498815422011-03-08T07:34:00.803-05:002011-03-08T07:34:00.803-05:00Is there some way that they can measure whether or...Is there some way that they can measure whether or not the rat is hearing a ringing sound? Kinda like how newborn babies are hooked up to those ear phone things to determine if they're deaf.Gennoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-59814548241412758122011-03-08T07:13:03.455-05:002011-03-08T07:13:03.455-05:00Hmmm. They can't pay volunteers much, but do o...Hmmm. They can't pay volunteers much, but do offer unlimited cheese.Grumpy, M.D.https://www.blogger.com/profile/09858110332436246760noreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-48517335760308427542011-03-08T07:11:44.023-05:002011-03-08T07:11:44.023-05:00As someone who has suffered with Tinnitus for year...As someone who has suffered with Tinnitus for years I'll gladly volunteer for the human trials!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5883634615775822475.post-47937648569330018532011-03-08T07:05:36.052-05:002011-03-08T07:05:36.052-05:00Maybe the experiment was done on a rat of NIMH?Maybe the experiment was done on a rat of NIMH?OMDGhttps://www.blogger.com/profile/17937425894428802591noreply@blogger.com